Pharmacological Inhibition of mTOR Kinase Reverses Right Ventricle Remodeling and Improves Right Ventricle Structure and Function in Rats
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منابع مشابه
Clinical manifestations of right ventricle involvement in inferior myocardial infarction
Abstract Background: Early diagnosis of right ventricle (RV) involvement in inferior myocardial infarction (Inf MI) is very critical. This study was performed to evaluate the clinical findings of Inf MI with or without RV infarction. Methods: From September 2010 to September 2012, 195 patients with definite diagnosis of Inf MI were evaluated in the Department of Cardiology, in Babol, north of...
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The pulmonary vasculature is an important site of renin-angiotensin metabolism. While angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers (collectively AIABs) have a role in left ventricular (LV) disease, the impact of AIABs on right ventricular (RV) function is unknown. AIAB use was determined by medication inventory during the Multi-Ethnic Study of Atherosclerosis ba...
متن کاملRight Ventricle and Exercise Capacity
Almost 3 quarters of a century ago, an experimental dog model, involving the electrocautery ablation of the free wall of the right ventricle (RV), served as the basis for the contention that the RV serves functionally as a passive conduit. Clearly, our understanding of the RV has evolved over subsequent decades, and the prognostic significance of RV dysfunction is now recognized in a wide array...
متن کاملDouble-chambered right ventricle.
Thirty (10.8%) of 279 patients undergoing correction of a ventricular septal defect (VSD) from January, 1972, to September, 1986, also had a double-chambered right ventricle (DCRV). Age at operation ranged from 1.3 to 18.8 years (mean, 6.7 +/- 4.5 years [+/- standard deviation]). Seventeen patients were male, and 13 were female. Two-dimensional echocardiography was used after 1978 in the initia...
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ژورنال
عنوان ژورنال: American Journal of Respiratory Cell and Molecular Biology
سال: 2017
ISSN: 1044-1549,1535-4989
DOI: 10.1165/rcmb.2016-0364oc